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Some patients experience stronger appetite suppression or more noticeable weight reduction while using tirzepatide, although individual results vary depending on medical history, consistency, and lifestyle habits

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For decades, we relied on the magic of glycemic control and control of hypertension to turn the tide of worsening DKD, only to see some patients with decent HbA1Cs still suffer from a decline of kidney function

Another important variable not captured was whether and the degree to which participants received substance use disorder treatment after diagnosis during the study window (see below for information on study window determination)